NIH funded postdoctoral position is immediately available for highly motivated individuals seeking to build a career in translational clinical research in lung diseases, especially in COPD, asthma and pneumonia. The candidate should have a PhD in the area of biochemistry or immunology. The lab is interested in translational research focusing on the transcription factor, Nrf2 pathway as an "immune-modulator". Recent report (Sci. Transl. Med., 2011; J. Clin. Invest. 2011) from the lab suggests that Nrf2 regulates oxidative stress and innate immune responses and thus, be a therapeutic target for COPD and other lung diseases . The postdoctoral fellow will be involved in ongoing clinical trials to measure the efficacy of Nrf2 activator in decreasing oxidative stress, inflammation, immune defenses against bacteria and virus and other biomarkers of pathophysiology of lung diseases. Previous experience in clinical biochemistry, handling blood and clinical biospecimens, PBMC/T cells, cell culture demonstrable from publications is mandatory. Details of research projects: http://web.jhu.edu/biswal. Send CV with names of 3 references by email to Shyam Biswal, PhD, Johns Hopkins University, School of Public Health. Email: biswallab@jhsph.edu
NIH funded research associate/postdoctoral position is immediately available for highly motivated individuals seeking to build a career in Cancer biology. The candidate should have a PhD in the area of cancer biology. The lab is interested in basic mechanistic and translational research focusing on the transcription factor, Nrf2 as a therapeutic target in cancer. Previous work from the lab has demonstrated that this transcription factor promotes tumor growth and confers resistance against cytotoxic chemotherapy and radiotherapy. This project seeks to understand the interaction of Nrf2-Keap1 pathway with other oncogenic signaling networks in tumor cells and develop novel approaches to target Nrf2-Keap1 axis in cancer. Details of research projects: http://web.jhu.edu/biswal. Individuals with a strong background in Oncology (preferably cancer immunology) and excellent productivity as demonstrated by publications are encouraged to apply. Send CV with names of 3 references by email to Shyam Biswal, PhD, Johns Hopkins University, School of Public Health. Email: biswallab@jhsph.edu
NIH funded postdoctoral position is immediately available for highly motivated individuals seeking to build a career in lung diseases. The candidate should have a PhD in the area of immunology preferably T cell biology. The lab is interested in basic mechanistic and translational research focusing on the transcription factor, Nrf2 pathway as an “immune-modulator”. Previous work from the lab has demonstrated that this transcription factor alters the susceptibility and severity of emphysema and other pulmonary diseases by activating the environmental cytoprotective stress response program. Recent report (Science Translational Medicine, 2011) from the lab suggests that Nrf2 regulates innate immune responses to bacterial infection in COPD. This project seeks to understand immune responses in the pathogenesis of COPD using mice model and clinical samples. Details of research projects: http://web.jhu.edu/biswal. Individuals with a strong background in immunology are encouraged to apply. Send CV with names of 3 references by email to Shyam Biswal, PhD, Johns Hopkins University, School of Public Health. Email: biswallab@jhsph.edu
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